In the film, Colonel William Stryker brainwashes and questions the imprisoned Magneto about Professor Xavier's mutant-locating machine, Cerebro. Stryker attacks the X-Mansion and brainwashes Xavier into locating every mutant on the planet to kill them. The X-Men must team up with the Brotherhood to prevent Stryker's worldwide genocide. It is the second installment in the X-Men film series.